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[11] [12] [84] In February 2026, a French man, Jean-Marc Laurent, filed what has been described as the first legal complaint related to paternal exposure to valproate, alleging that his child developed neurodevelopmental disorders after he had been treated with the drug prior to conception

Other studies such as in vitro studies, animal experiments, observational studies, studies with duration below two weeks, case reports and studies without a control group were excluded from this meta-analysis