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Regulatory monitoring has recorded two serious adverse events in the FDAs FAERS database (2021, 2023) and one life-threatening event in the CAERS database

The key findings of the 36 studies was the mechanism of action is angiogenesis, so blood flow, creating new blood flow to an area, collagen synthesis, anti-inflammatory effects, and neuroprotection

Common issues include notes that describe general therapy rather than plan development activities, or claims submitted by physicians rather than qualifying non-physician professionals

For maintenance, those with pernicious anaemia may need injections for life, while others might transition to a less frequent schedule or use tablets if the deficiency is diet-related