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NAD(P)H dehydrogenase (NQO1), an NRF2-targeted enzyme possessing broad cytoprotective functions [30], was upregulated in the skin tissues of IMQ-induced psoriatic mice treated with SFN, whereas NRF2-deficient mice exhibited minimal expression (Fig

Oil extraction was carried out for a period of six hours (hrs)

doi: 10.1371/journal.pone.0060921, 34

Valerio M, Awad AB (2011) -sitosterol down-regulates some pro-inflammatory signal transduction pathways by increasing the activity of tyrosine phosphatase SHP-1 in J774A.1 murine macrophages