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It is important to emphasise that these proposals are based almost entirely on preclinical data principally in vitro (cell culture) experiments and animal studies and have not been reliably demonstrated in robust human clinical trials: Stimulation of follicle enlargement: Laboratory studies suggest GHK-Cu may increase hair follicle size, potentially counteracting the miniaturisation associated with androgenetic alopecia (pattern hair loss), though this has not been confirmed in humans

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In addition to wound healing studies in mice, clinical studies have been done on the effect of GHK-Cu on skin regeneration, which show a more rapid healing process and better skin conditions with GHK-Cu in the skin cream [3, 17]