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[DOI] [PubMed] [Google Scholar] 10.Stephens F.B., Wall B.T., Marimuthu K., Shannon C.E., Constantin-Teodosiu D., Macdonald I.A., Greenhaff P.L

The density indicates some flexibility at R471 in both the inward-facing and ipratropium-bound structures, but both are pointing down towards the extracellular side and wedged between S157 and S467, preventing the H-bond network we observe in the occluded conformation (Fig