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doi:10.3389/fonc.2018.00622

For vaccine induced protection against mycobacterial infections, CD4+ cells are vital and multiple studies have demonstrate that CD8+ cells play critical role in controlling mycobacterial infections via perforin, granzymes, and granulysin ( ex-vivo result of the IcL group is more difficult to interpret as the primed PBMCs indicated higher survival rate for MAP compared to macrophage alone or incubated with unprimed PBMCs

Collectively, our findings demonstrate a key role for regulation of redox homeostasis in pathogen survival and disease

Continuing therapy or adjusting your regimen ensures sustained benefits