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Women who are pregnant, planning pregnancy, or breastfeeding should consult their obstetricians before considering glutathione therapy, and most healthcare providers recommend avoiding elective supplementation during these periods

Although both dysregulated hepatic glutathione homeostasis and TNF overproduction are critically involved in the development of NAFLD, whether they can be synergistically implicated in hepatocyte death remains to be clearly defined

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It is also linked to the limited connectivity between islands, which the government has tried to address by implementing the Maritime Highway ( Tol Laut ) project (Handoko et al., 2020)