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As noted above, chemotherapy and radiotherapy cause an increase in intracellular ROS that can lead to apoptosis 92,93 via extrinsic or intrinsic pathways 94,95

The immune system The immune systems primary responsibility is to distinguish between harmful and harmless signals and respond appropriately

Leukemia 15 (10), 16331640

Reported prevalence varies across populations and study designs, with estimates ranging from approximately one-third to over one-half of respondents admitting to the use of performance-enhancing substances, including anabolicandrogenic steroids (6)