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At rest, blockade of these two channels reduces CBF by approximately 15%, while activation of these two channels increases CBF by approximately 40% (McNeish et al., 2006

416 OhtsukiS.SchaeferO.KawakamiH.InoueT.LiehnerS.SaitoA.et al (2012)

44 have shown that the number of EPCs is decreased in relation to the cumulative number of Framingham risk factors and that the number of EPCs is correlated with endothelial function measured by FMD