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The main challenge in immunotherapy lies in converting cold tumors, which are resistant to the immune response, into hot tumors, which are more likely to respond to ICIs [136]

In contrast, neither Cdkn1a nor Nupr1 expression was significantly altered in OLs at 7 days post-lesion (dpl) or 28 dpl (demyelination and remyelination, respectively) following LPC injection, compared to saline-injected controls (Fig

Accordingly, the luminal membrane of bronchial epithelial cells harbors multiple ABC transporters involved in detoxification and drug resistance (ABCB1/Pgp, ABCC2-6, ABCC10-11) (Chai et al

Peptides like ipamorelin come with zero downtime