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Some studies showed significant reductions, while others reported no effect in the general T2DM population unless baseline FBG was high ( 8.0 mmol/L)

The burden of glycated proteins can be estimated from the fact that diabetic individuals are more than 50% susceptible in developing cognitive disorders as compared to non-diabetic persons ( Previously, people used immunological techniques such as ELISA and immunoblotting for detection of glycated protein adducts which frequently led to overestimation of AGEs due to conversion of Amadori products into carboxy methyl lysine or pentosidines (Suzuki et al., 2022)

Therefore, chlorophyllin, a GSTP1 inhibitor, seems an interesting compound due to its safety and role in metastasis-related processes

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