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BPC-157 upregulates survival genes (Akt1, KRAS, Src, Foxo1), reduces inflammatory mediators (IL-6, TNF-, NOS2, NFB), scavenges reactive oxygen species through its four carboxylic groups, activates vascular bypass pathways, and maintains blood flow despite vessel occlusion

Epitalon-treated oocytes, however, showed reduced Annexin-V signals and a lower proportion of apoptotic cells, indicating that the peptide reduces apoptotic susceptibility in aged oocytes [2]