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b, k 3 = 0.01230 s 1 and k 4 = 0.00035 s 1 (and the original values were 0.01140 s 1 and 0.00026 s 1 , respectively), 4) the k 3 and k 4 for 1a R -IN-8 were calculated based on a new experiment (2, 5, 10 nM): k 3 = 0.02453 s 1 and k 4 = 0.00035 s 1 (and the values for the first experiment were 0.02617 s 1 and 0.00034 s 1 , respectively), and finally 5) all four values for 6 S,S -IN-8 were determined based on new experiments (100, 300, 1000 nM on the JNK C116S and 3, 6 nM on the JNK WT surface): k 1 = 129000 M 1 s 1 , k 2 = 0.05387 s 1 , k 3 = 0.00630 s 1 , k 4 = 0.00004 s 1 (and the original values were k 1 = 164000 M 1 s 1 , k 2 = 0.03460, k 3 = 0.01064, k 4 = 0.00006)