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van Seventer and Hochberg, 2017) and procedures involving biomaterials or medical devices (Arciola et al., 2018

Instead, it is measured through forensic testing

Recommendation for clinical practice: Patients with type 2 diabetes treated with Metformin, especially those with concomitant use of proton pump inhibitors, should be monitored for vitamin B12 deficiency and/or hyperhomocys- teinemia