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179 However, in some cases, the downregulation or loss of function of DNMT3B is also related to the occurrence of tumors

doi: 10.3389/fphar.2020.01257 30 ManaloTABiermannHDPatilDHMehtaA

Inhibitors of GPX4 effectively trigger iron and lipid peroxidation-dependent cell death, demonstrating considerable antineoplastic effects across various cancers, including nasopharyngeal carcinoma [128], non-small cell lung carcinoma (NSCLC) [129, 130], pancreatic adenocarcinoma [131], and melanoma [132]