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NAC as a Pharmacological Chaperone NAC is hypothesized to bind and stabilize misfolded proteins and route them correctly within the cell, thereby facilitating their activity by acting as a pharmacological chaperone

While the formation of 5-(3,4-dihydroxyphenyl)--valerolactone from (+)-catechin by intestinal bacteria has already been described by Das (79), only more recently the contributing colonic microbiota have been characterized

The analyses were conducted by fitting GSH, GSH:GSSG ratio, and GPX as continuous variables as well as categorizing them into tertiles