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Diselenide-pemetrexed assemblies for combined cancer immuno-, radio-, and chemotherapies

Sternberg & Rifkin, 1979)

To that end, an E3 ligase activity-deficient mutant of UBR5 was generated by mutating the critical residue cysteine 2768 to alanine (UBR5C2768A, Mut-UBR5), as previously reported 39

Although PI3K pathway inhibitors reduce cancer growth, they could accidentally increase tumor invasion by inducing reprograming of mitochondrial trafficking, OXPHOS, and promoting cell motility (203)