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14,15-EET inhibited rat mesenteric arterial endothelial senescence, down-regulated p53 expression in aged endothelial cells and improved the impaired endothelium-dependent vasodilatation in aged rats through activation of mTORC2/Akt signaling pathway (Yang et al., 2014)

DILI is categorized into intrinsic and idiosyncratic types

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On the day of measurement, mice were orally administered metformin at a dose of 150 mg/kg 2 h after the start of fasting, and FDG was injected 2 h later