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Oxidation of proteins, lipids, and DNA has been implicated in cataractogenesis [6973]

Neurotransplantation therapy, relatively intensively studied in Lurcher mice [114, 220,221,222,223,224,225,226], as well as pharmacotherapy showed rather inconsistent or pessimistic results regarding motor improvement [223], with the exception of mesenchymal stem cell grafting in newborn Lurchers reducing Purkinje cell loss [227]

Muller, O., Lu, G., Jahn, A

In contrast, miR-21, a well-characterized oncomiR, is overexpressed in RCC, promoting tumor growth, invasion, and poor prognosis by downregulating PTEN, which subsequently activates AKT and mTOR (204, 205)