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Virus-induced hyper-inflammation with complement activation in kidney tissue could inflict focal segmental glomerulo-sclerosis with glomerular involution and lead to AKI 138

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Adrenergic receptor 1 stimulates Ca 2+ influx via activation of phospholipase C followed by increase in intracellular concentration of inositol triphosphate (IP 3 ) and diacylglycerol (DAG)