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To evaluate NRF2-dependent regulation of these genes, we generated two KEAP1 -mutant NSCLC cell lines (A549 and NCI-H460) stably integrated with a doxycycline (dox)-inducible shRNA targeting NRF2

110 :E113-E22 8

(6) Current nanozyme delivery methods, such as injections, microneedle patches, and nanoparticle suspensions, have limitations, including pain, insufficient drug loading, and short residence times on the wound surface