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[52] intranuclear accumulation of glutathione may modulate the thiol/disulfide redox status of nuclear proteins and control chromatin compacting and decondensation

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In esophageal cancer and salivary adenoid cystic carcinoma, GPx1 expression facilitates invasion, migration, proliferation, and resistance to cisplatin

Therefore, the pH of the interstitial fluid in muscle tissues can drastically change in response to muscle contraction and can also be a marker of acidbase conditions in muscle tissue