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Monzo-Beltran, L

Although speculative, metabolites in the kynurenine pathway are critical immunomodulators, which contribute, along with arginine (one of the most affected pathways identified herein), to immunosuppressive activity of dendritic cells (48) and to CD8 + T cell suppression in breast cancer (49, 50)

Thiostrepton activates the STAT3GPX4 signalling pathway Next, we sought to decipher the molecular mechanisms that may be responsible for the activation of ferroptosis by TST