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Also, serum total protein in male animals was reduced (2000 and 3000 mg/kg) in the treated male rats while an elevated low density lipoprotein (3000 mg/kg) was obtained in female animals

On the one hand, the inhibition of ferroptosis in intestinal tissues by OTSSP167, a MELK inhibitor, alleviates colitis and abrogates the occurrence and progression of CAC by reducing M1 macrophage polarization, macrophage infiltration, downregulating the secretion of pro-inflammatory factors, and significantly repairing intestinal damage

If you experience these symptoms, consult your doctor to determine the underlying cause and explore potential treatment options