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It has been reported that N-acetyl Cysteine significantly improved (based on the Montgomery Asberg Depression Rating Scale, MADRS) state of patients with bipolar disorder (Berk et al

Notwithstanding the promise of ferroptosis in preclinical models, its clinical translation faces significant hurdles, particularly in drug delivery and on-target/off-tumor toxicity

UA is now recognized as a mitochondrial modulator that enhances mitophagy, although its molecular target remains to be determined

[DOI] [PubMed] [Google Scholar] McDowell C.M., Kizhatil K., Elliott M.H., Overby D.R., van Batenburg-Sherwood J., Millar J.C.Stamer W.D