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Opioid Classifications and Drug Schedules To ensure a safe environment for patients, reduce the risk of diversion or misuse, and ensure compliance with federal laws and regulations, Nurse Practitioners and clinicians need to understand both the DEA Schedules and Opioid Classification

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In one study, the clearance of free valproate was decreased by 50% in seven patients with cirrhosis and by 16% in four patients with acute hepatitis, compared to six healthy subjects