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Late diagnosis is increasingly common, particularly for adults who grew up when awareness of these conditions was more limited

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The repair cycle starts with the monomerization of phosphorylated dimeric PSII complex in grana stacks and is continued by dephosphorylation of D1, D2 core proteins and CP43 most probably while passing through only loosely stacked non-appressed stroma-exposed thylakoids

Thus, combining anti-VEGF medications with targeted inhibition of NRP2 effectors offers a promising approach to enhance efficacy in cancer