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Hyaluronic Acid is a naturally occurring glycosaminoglycan found throughout the skin and connective tissues, where it plays a critical role in maintaining hydration and structural integrity

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The latter possibility is consistent with the report that KLF9 acts as a transcriptional mediator of glucocorticoid-regulated, KLF9 family member KLF2 in macrophages to promote inflammation (Chinenov et al., 2014)