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Summary and outlook PROTACs have emerged as a transformative modality in TPD, yet their clinical translation is increasingly contingent upon innovations in delivery systems

To contextualize the complexity of these interactions, we present an integrated mechanistic framework (Fig

Serum calcium, magnesium, copper and zinc and risk of cardiovascular death

Safety profiles of COVID-19 vaccines should be closely monitored in real time during human efficacy trials, especially for vaccine modalities that may have a higher theoretical potential to cause immunopathology (such as inactivated whole-virus formulations or viral vectors) 64,65