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Aberrant histone acetylation promotes chromatin relaxation and transcriptional activation of oncogenes and stemness-associated factors, facilitating uncontrolled proliferation, invasive growth and resistance to therapy (Hou et al., 2017

In addition to pharmacological compounds, genetic modifications targeting regulators of the system x c can induce ferroptosis

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In response to RQ3: How does the proposed multi-class transformer pipeline compare, in predictive quality, with a zero-shot large-language-model baseline