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Simultaneously, IFN- disrupts the blood-brain barrier (BBB), thus facilitating the entry of peripheral inflammatory mediators into the CNS and contributing to neuroinflammation and neurological symptoms [48, 49]

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Finding the ulcer-related underlying cause of the bleeding is the first treatment step

"Vitamin C-lipid metabolites: Uptake and retention and effect on plasma C-reactive protein and oxidized LDL levels in healthy volunteers." Med Sci Monit