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Physical symptoms: Lower abdominal cramps and pelvic pain Bloating and water retention Breast tenderness Headaches or migraines Unexplained fatigue Lower back pain Psychological and emotional symptoms: Mood swings Anxiety or mild depression Difficulty concentrating Food cravings Menstrual Cramps (Dysmenorrhea) Period pain, medically known as dysmenorrhea, is caused by elevated levels of prostaglandins hormone-like chemicals that trigger uterine contractions to expel the lining

Several experiments involved only female mice, fixed intermittent exposure and limited sample sizes