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Testing different domains of an interacting protein to see which one binds to your protein of interest

There is an interlinking mechanism behind immunomodulation that is controlled by oxidative stress or vice versa (Namoju et al., 2021)

Subjects were seen at 6 months intervals after enrollment

Children aged 412 years were diagnosed with ASD according to DSM criteria, both boys and girls were included, and the study explicitly excluded participants with major psychiatric comorbidities such as ADHD, depressions, bipolar disorder, anxiety disorders, epilepsy, severe intellectual disabilities, or recent antipsychotic use, ensuring relative homogeneous sample focused on irritability