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Validating urine-based biomarkers (e.g., glomerular cell-derived exosomal ferroptosis regulators, and 4-HNE metabolites) or circulating signatures that correlate with IgA nephropathy disease activity, pathological severity, or response to interventions is urgently needed to guide clinical trial design and patient stratification

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Burlingame, CA) or biotin-conjugated anti-rat IgG antibody (F4/80: Vector Laboratories) in 0.1 M PBS at 22 2 C for 30 min

A combined EPA-DHA fish oil supplement should be taken by anyone with gallstones, or risk factors for the development of gallstones