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1983 Oct 10;258(19):11727-30

10.1016/j.cardiores.2004.12.027 5 CadenasS

The supernatant was removed after centrifugation at 100 g for 1 min at room temperature

The nanoencapsulation strategy discussed in this article overcomes physiological barriers by optimizing particle size and surface properties to avoid rapid clearance, reduces immune recognition through surface modification, and employs targeted strategies to enhance biological distribution and tumor penetration