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DOI : 10.1186/s13020-025-01096-z

10.1007/s40089-016-0184-9 166 SainiS.KumarP.SharmaN

Collectively, these PK features create mismatches between mechanistic antioxidant promises and clinical efficacy, especially when ascent is rapid and symptom onset precedes peak systemic levels

Omaveloxolone mildly increased serum aminotransferase activity while also significantly improving liver histology (i.e., showing hepatoprotective effects) in an animal model of metabolic dysfunction-associated steatohepatitis (formerly known as nonalcoholic steatohepatitis) [43]