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Notably, the liver PARP activity of patients with severe NAFLD is much greater than that of patients with simple steatosis, suggesting that aberrant PARP-1 activation may contribute to the downregulation of liver PPAR expression in these individuals (115)

Quinoa could protect against bone loss in the OVX rats by altering the composition of GM and restoring the damaged intestinal barrier, thereby ameliorating bone microstructure deterioration and bone metabolism disturbances (162)