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4 Cutaneous lesions exhibit erythema, variable degrees of alopecia, scaling, crusting, and lichenification, which are commonly symmetric and most often affect the head (periocular, perioral, and pinnae

B cell activation in MG occurs through coordinated costimulatory signals from helper T cells and stimulation by IL-21 and IL-6, driving differentiation into plasma cells under Blimp-1 transcriptional control (29)

Krajewski MP, Kanawati B, Fekete A, Kowalski N, Schmitt-Kopplin P, Grill E (2013) Analysis of Arabidopsis glutathione-transferases in yeast

In hyperuricemia models, this process activates the innate immune system, resulting in elevated serum levels of LPS and pro-inflammatory cytokines like tumor necrosis factor-alpha (TNF-) (Xu D