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A muscle-preservation strategy commonly includes: Regular resistance training Adequate dietary protein A reasonable rate of weight loss Enough calories to support recovery Sleep and stress management Body-composition measurements Adjustments when strength or lean mass declines A body-composition peptide should not be used as a substitute for these measures

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Informed by recent studies from 2024-2025, future research should prioritize the development of disease-specific ferroptosis biomarkers, optimization of combination therapy regimens, creation of next-generation modulators with enhanced cell-type specificity and pharmacokinetic properties, and elucidation of ferroptosis crosstalk with other regulated cell death pathways (152)