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21: 31236 Lorber A, Baumgartner WA, Bovy RA, et al

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demonstrated that elevated salivary cf-mtDNA levels serve as an independent predictor of poor prognosis in head and neck squamous cell carcinoma [107]

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In addition, miR-155 downregulates STAT3 and SOCS1 in mouse macrophages, resulting in the upregulation of pro-inflammatory cytokines TNF and IL-1b and the downregulation of anti-inflammatory cytokine IL-10 [41]

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