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Similarly, prolonged bruising has also been documented in the malar and zygomatic region, where large vessels such as transverse facial artery and zygomaticofacial artery are located, as well as around the perioral area along the course of the facial artery and vein (Figure 8)

In this Review, we will focus on three different non-neuronal cell types found in the brain, the microglia, mast cells and astrocytes and their interaction with histamine