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This doesnt cause autism by itself but it creates a metabolic environment in which the developing brain becomes: more sensitive to stress slower to regulate serotonin more rigid in emotional and cognitive patterns more vulnerable to inflammation and immune activation Undermethylation also reduces the ability to neutralize excess copper and manage oxidative stress, making both of those patterns far more likely to occur

In response to the muscle damage and supplementation, circulating levels of free iron (that could possibly react to form hydroxyl radicals) were increased, lactate dehydrogenase and creatine kinase, markers of protein breakdown and damage, were elevated in the supplemented group as well as an increase in markers for oxidative stress

Concomitant use with nitroglycerin can lead to increased blood levels of nitroglycerin, causing a severe drop in blood pressure

Thompson et al., 2023)