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Dominguez Gutierrez PR, Kwenda EP, Donelan W, OMalley P, Crispen PL, Kusmartsev S

The Interplay between Pathophysiological Pathways in Early-Onset Severe Preeclampsia Unveiled by Metabolomics

Nutrient interactions Together with several B-vitamins (i.e., folate, vitamin B 12 , vitamin B 6 , and riboflavin), choline is required for the metabolism of nucleic acids and amino acids, and for the generation of the universal methyl group donor, S-adenosylmethionine (SAM) ( Figure 4 )