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doi: 10.1152/physrev.00008.2013

Comparison of hypoxia-inducible factor-1 expression before and after transcatheter arterial embolization in rabbit VX2 liver tumors

The LASSS-stimulated mechanism is un-related to prevention of HGF nitration because all of the findings (shown in Figure 1e right panel, bars 810 and Figure 2a) were obtained under nitration-free conditions (omitting peroxynitrite treatment)

Some human trials suggest oral glutathione at 250500 mg/day may reduce melanin production in sun-exposed areas and lighten dark spots, though results are moderate and vary by individual