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Dysregulation of these pathways contributes to various cell death diseases, such as cancer, neurodegenerative diseases, and ischemic injury, where either evasion or excessive activation of cell death disrupts normal function

Further research on ALOX12/15 inhibitors is crucial to understanding their therapeutic potential and their role in MDSCs ferroptosis, which could enhance anti-tumor immunity and cancer immunotherapy efficacy

Many of Dr

Interleukin-IL, Monocyte chemoattractant protein-MCP-1, Matrix metalloproteinase 9- MMP-9, Partial prothrombin time (APTT), Prothrombin time (PT), Thrombin time (TT), Interferon-gamma - IFN- , Interferon-gamma receptor 1-IFNGR1, TNF- Tumor Necrosis Factor , MIC- Minimum Inhibitory Concentration, Methylglyoxal -MGO, Protein tyrosine phosphatase 1B -PTP1B, Neutrophil extracellular trap formation- NETosis