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Besides these increments in BCAAs and ArAAs, we also found reduced plasma levels of arginine and glutamine in children with obesity, in line with previous studies reporting disrupted nitrogen metabolism through the urea cycle and impaired production of nitric oxide [4]

10.58332/scirad2024v3i4a04 144 TanX.WangL.SmithW

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Preserved lean muscle mass while reducing fat mass Studies showed that NNMT inhibition selectively reduced adipose tissue without negative effects on skeletal muscle mass, suggesting a favorable body composition profile