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Malnutrition and weight loss Suicidal thoughts Sleeping problems Drug dependence, which may lead to accidents or even loss of life due to overdose Violent behavior To add to the risks above, drug users who resort to breathing in substances end up with a distorted self-image

A partially purified leaf enzyme with DHAR activity was subsequently reported, but was considered likely to be cytosolic (Foyer and Halliwell 1977)

patients often experience fluctuating or persistent symptoms varying significantly in intensity over time, making the condition challenging to manage