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Here, we report a case of combining an anti-VGFR (bevacizumab) and immune checkpoint inhibitor (atezolizumab) with high vitamin C in a patient with unresectable hepatocellular carcinoma (HCC)

10.3390/molecules25143146

Local metformin release further downregulated PD-L1, enhancing antitumor effects

He first developed painful bilateral toe tingling and numbness one year prior to presentation, with symptoms gradually ascending to his shins in a symmetric fashion