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It has to be mentioned that KO mice for IGF-1 gene are not viable and studies in such mice have to be done in the first days of life, and thus results are not very conclusive as metabolism is not properly established at this stage [129, 228]

These include: Older adults, as they absorb B12 less easily Vegetarians and vegans, because B12 is mostly in animal products People with stomach problems like celiac disease or Crohns disease Those who have had gastric bypass surgery Knowing these risk factors helps find who might need to check their B12 levels

Instead, it exists as a research compound, which means its quality, purity, and concentration can vary significantly between suppliers

For example, when a fieldworker has measured the weight and length of a child, a supervisor or scientist will undertake the same measurement and compare their findings with that of the fieldworker