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Based on similar clinical presentations and the lack of objective tests that demonstrate causality, it is hypothesized that chronic cannabis use can unmask symptoms in genetically predisposed individuals and cause hyperemesis.14 In addition, THC concentration in cannabis products has increased exponentially over time, which could also explain the paradoxical effects of cannabis use being an antiemetic at low doses and proemetic in high concentrations.53 Clinical subtypes of cyclic vomiting syndrome Recognizing the different CVS subtypes is possible through a detailed clinical history

The inotropic effect is augmented by caffeines inhibition of phosphodiesterase, which increases the concentration of cAMP in the myocardium and enhances the intracellular influx of calcium ions into cardiomyocytes

Mitochondrial dynamics and its involvement in disease

(2025) 104:e42046